TY - JOUR
T1 - A case of mucoepidermoid carcinoma of the nasopharynx
AU - Tachino, Hirohiko
AU - Takakura, Hiromasa
AU - Ito, Shinsuke
AU - Nakazato, Akira
AU - Nakanishi, Akihito
AU - Abe, Hideharu
AU - Ishida, Masayuki
AU - Fujisaka, Michiro
AU - Imura, Johji
AU - Shojaku, Hideo
N1 - Publisher Copyright:
© 2018 Society of Practical Otolaryngology. All rights reserved.
PY - 2018
Y1 - 2018
N2 - Salivary gland-Type neoplasms arising in the nasopharynx are rare, accounting for less than 2% of all nasopharyngeal neoplasms. Herein, we report a case of mucoepidermoid carcinoma (MEC) of the nasopharynx, and along with a review of the literature, discuss the therapeutic strategies depending on the histological and radiological findings. The patient was a 78-year-old man. He had first noticed a mass on the left side of the neck 9 months earlier, which began to gradually increase in size. Clinical examination revealed a tumorous lesion in the left nasopharynx. Both nasopharyngeal and cervical biopsies revealed the diagnosis of MEC, so that the patient was diagnosed as having nasopharyngeal MEC (T1N2M0, stage III). After induction chemotherapy with docetaxel plus cisplatin and fluorouracil (TPF), endoscopic removal of the tumor was undertaken via the endonasal approach, with bilateral neck dissection. Furthermore, postoperative chemoradiotherapy was also administered. Until now, two years six months since the completion of treatment, the patient has shown no evidence of local recurrence or distant metastasis. Based on our experience, it seems that our treatment approach is one of the valid treatment options for nasopharyngeal MEC.
AB - Salivary gland-Type neoplasms arising in the nasopharynx are rare, accounting for less than 2% of all nasopharyngeal neoplasms. Herein, we report a case of mucoepidermoid carcinoma (MEC) of the nasopharynx, and along with a review of the literature, discuss the therapeutic strategies depending on the histological and radiological findings. The patient was a 78-year-old man. He had first noticed a mass on the left side of the neck 9 months earlier, which began to gradually increase in size. Clinical examination revealed a tumorous lesion in the left nasopharynx. Both nasopharyngeal and cervical biopsies revealed the diagnosis of MEC, so that the patient was diagnosed as having nasopharyngeal MEC (T1N2M0, stage III). After induction chemotherapy with docetaxel plus cisplatin and fluorouracil (TPF), endoscopic removal of the tumor was undertaken via the endonasal approach, with bilateral neck dissection. Furthermore, postoperative chemoradiotherapy was also administered. Until now, two years six months since the completion of treatment, the patient has shown no evidence of local recurrence or distant metastasis. Based on our experience, it seems that our treatment approach is one of the valid treatment options for nasopharyngeal MEC.
KW - Chemoradiotherapy
KW - Induction chemotherapy
KW - Intranasal endoscopic removal
KW - Mucoepidermoid carcinoma
KW - Nasopharyngeal carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85045346787&partnerID=8YFLogxK
U2 - 10.5631/jibirin.111.235
DO - 10.5631/jibirin.111.235
M3 - 学術論文
AN - SCOPUS:85045346787
SN - 0032-6313
VL - 111
SP - 235
EP - 241
JO - Practica Otologica
JF - Practica Otologica
IS - 4
ER -