TY - JOUR
T1 - A case of Legionella pneumophila pneumonia followed by invasive aspergillosis
AU - Saijo, Tomomi
AU - Izumikawa, Koichi
AU - Takazono, Takahiro
AU - Kosai, Kosuke
AU - Kurihara, Shintaro
AU - Nakamura, Shigeki
AU - Imamura, Yoshifumi
AU - Miyazaki, Taiga
AU - Seki, Masafumi
AU - Kakeya, Hiroshi
AU - Yamamoto, Yoshihiro
AU - Yanagihara, Katsunori
AU - Miyazaki, Yoshitsugu
AU - Fukushima, Kiyoyasu
AU - Kohno, Shigeru
PY - 2008
Y1 - 2008
N2 - We report a rare case of Legionella pneumophila pneumonia followed by invasive aspergillosis (IA). Legionellosis was ameliorated by the administration of ciprofloxacin, erythromycin, and corticosteroid as adjunctive therapy. Although intravenous administration of the corticosteroid was effective at reducing severe inflammation due to legionellosis, IA occurred at 12 days after admission. Combination therapy with micafungin and voriconazole was effective in this case; however, it remains necessary to exercise caution when making decisions regarding indications for corticosteroid use and observation in the treatment of severe pneumonia patients.
AB - We report a rare case of Legionella pneumophila pneumonia followed by invasive aspergillosis (IA). Legionellosis was ameliorated by the administration of ciprofloxacin, erythromycin, and corticosteroid as adjunctive therapy. Although intravenous administration of the corticosteroid was effective at reducing severe inflammation due to legionellosis, IA occurred at 12 days after admission. Combination therapy with micafungin and voriconazole was effective in this case; however, it remains necessary to exercise caution when making decisions regarding indications for corticosteroid use and observation in the treatment of severe pneumonia patients.
UR - http://www.scopus.com/inward/record.url?scp=54449099987&partnerID=8YFLogxK
M3 - 学術論文
C2 - 18806346
AN - SCOPUS:54449099987
SN - 1344-6304
VL - 61
SP - 379
EP - 381
JO - Japanese Journal of Infectious Diseases
JF - Japanese Journal of Infectious Diseases
IS - 5
ER -
