TY - JOUR
T1 - A case of intravascular large b-cell lymphoma (ivlbcl) with no abnormal findings on chest computed tomography diagnosed by random transbronchial lung biopsy
AU - Kaku, Norihito
AU - Seki, Masafumi
AU - Doi, Seiji
AU - Hayashi, Tomayoshi
AU - Imanishi, Daisuke
AU - Imamura, Yoshifumi
AU - Kurihara, Shintaro
AU - Miyazaki, Taiga
AU - Izumikawa, Koichi
AU - Kakeya, Hiroshi
AU - Yamamoto, Yoshihiro
AU - Yanagihara, Katsunori
AU - Tashiro, Takayoshi
AU - Kohno, Shigeru
PY - 2010
Y1 - 2010
N2 - A 58-year-old woman was admitted with refractory fever despite receiving broad-spectrum antibiotics. She had hypoxemia, severe anemia, elevated levels of serum lactic dehydrogenase and soluble interleukin-2 receptor, and a positive direct Coombs test, which suggested an underlying autoimmune hemolytic anemia (AIHA). Chest computed tomography (CT) showed no abnormal findings, but she had hypoxia, and her alveolar-arterial oxygen difference (A-aDO2) was increased. A random transbronchial lung biopsy (TBLB) was performed, and pathological analysis showed massive proliferation of tumor cells in the lumina of the small vessels. Intravascular large B-cell lymphoma (IVLBCL) was diagnosed, and her general status improved after chemotherapy.
AB - A 58-year-old woman was admitted with refractory fever despite receiving broad-spectrum antibiotics. She had hypoxemia, severe anemia, elevated levels of serum lactic dehydrogenase and soluble interleukin-2 receptor, and a positive direct Coombs test, which suggested an underlying autoimmune hemolytic anemia (AIHA). Chest computed tomography (CT) showed no abnormal findings, but she had hypoxia, and her alveolar-arterial oxygen difference (A-aDO2) was increased. A random transbronchial lung biopsy (TBLB) was performed, and pathological analysis showed massive proliferation of tumor cells in the lumina of the small vessels. Intravascular large B-cell lymphoma (IVLBCL) was diagnosed, and her general status improved after chemotherapy.
KW - Autoimmune hemolytic anemia (aiha)
KW - Computed tomography
KW - Fever of unknown origin (fuo)
KW - Intravascular large b-cell lymphoma (ivlbcl)
KW - Rituximab
KW - Transbronchial lung biopsy (tblb)
UR - http://www.scopus.com/inward/record.url?scp=78650374301&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.49.3986
DO - 10.2169/internalmedicine.49.3986
M3 - 学術論文
C2 - 21173545
AN - SCOPUS:78650374301
SN - 0918-2918
VL - 49
SP - 2697
EP - 2701
JO - Internal Medicine
JF - Internal Medicine
IS - 24
ER -