A Case of Colon Carcinosarcoma in Ulcerative Colitis

Kazuma Ito, Ryuichi Kuwahara, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Takako Kihara, Seiichi Hirota, Kozo Kataoka, Naohito Beppu, Motoi Uchino, Masataka Ikeda, Hiroki Ikeuchi

Research output: Contribution to journalArticlepeer-review

Abstract

A 70-year-old woman was diagnosed with ulcerative colitis (UC) at 54 years of age. The patient had been in remission with treatment with 5-aminosalicylic acid. In June 2021, she was diagnosed with sigmoid colon cancer by lower gastrointestinal endoscopy, which was performed to investigate diarrhea. In August of the same year, laparoscopic-assisted total proctocolectomy with ileal J-pouch-anal canal anastomosis was performed. The tumor showed a mixture of carcinoma and sarcoma components, and the pathological result was carcinosarcoma, type 2, 35×30 mm, pT3(SS), INFb, Ly1a, V1b, Pn1b, pN2a, pStage IIIb (9th edition of the Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma). CT performed in the first month after surgery revealed multiple liver metastases, which were not seen before surgery. Chemotherapy (mFOLFOX+panitumumab) was started in September of the same year, but the patient passed away 6 months after the surgery. This is an extremely rare case of colorectal carcinosarcoma in a patient with UC.

Translated title of the contribution潰瘍性大腸炎に結腸癌肉腫を合併した1 例
Original languageEnglish
Pages (from-to)348-355
Number of pages8
Journalthe japanese journal of gastroenterological surgery
Volume56
Issue number6
DOIs
StatePublished - 2023

Keywords

  • carcinosarcoma
  • colorectal cancer
  • ulcerative colitis

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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