A case of autoimmune autonomic ganglionopathy with prolonged delirium

Shinya Uenishi; Shun Takahashi; Yoshiaki Nakayama; Yasuhiro Hiwatani; Shunya Nakane; Tomikimi Tsuji; Satoshi Ukai

doi:10.1016/j.ajp.2018.11.003

A case of autoimmune autonomic ganglionopathy with prolonged delirium

Shinya Uenishi^*, Shun Takahashi, Yoshiaki Nakayama, Yasuhiro Hiwatani, Shunya Nakane, Tomikimi Tsuji, Satoshi Ukai

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Autoimmune autonomic ganglionopathy (AAG) is a rare acquired immune-mediated disorder that leads to autonomic failure. It is sometimes complicated by mental and behavioral symptoms. We report a case of 72-year-old male with AAG who was admitted to the psychiatric department for prolonged severe delirium. Repeated loss of consciousness attributed to severe orthostatic hypotension disturbed recovery from delirium. In addition, intracerebral hemorrhage occurred during hospitalization, and this cerebrovascular event may have been substantially affected by unstable blood pressure due to AAG. This case suggests importance of differential diagnosis of AAG in patients with mental and behavioral symptoms accompanying severe autonomic failure.

Original language	English
Pages (from-to)	8-9
Number of pages	2
Journal	Asian Journal of Psychiatry
Volume	39
DOIs	https://doi.org/10.1016/j.ajp.2018.11.003
State	Published - 2019/01

Keywords

Autoimmune autonomic ganglionopathy
Autonomic failure
Delirium
Elderly
Ganglionic nicotinic acetylcholine receptor autoantibody

ASJC Scopus subject areas

General Psychology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ajp.2018.11.003

Cite this

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title = "A case of autoimmune autonomic ganglionopathy with prolonged delirium",

abstract = "Autoimmune autonomic ganglionopathy (AAG) is a rare acquired immune-mediated disorder that leads to autonomic failure. It is sometimes complicated by mental and behavioral symptoms. We report a case of 72-year-old male with AAG who was admitted to the psychiatric department for prolonged severe delirium. Repeated loss of consciousness attributed to severe orthostatic hypotension disturbed recovery from delirium. In addition, intracerebral hemorrhage occurred during hospitalization, and this cerebrovascular event may have been substantially affected by unstable blood pressure due to AAG. This case suggests importance of differential diagnosis of AAG in patients with mental and behavioral symptoms accompanying severe autonomic failure.",

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author = "Shinya Uenishi and Shun Takahashi and Yoshiaki Nakayama and Yasuhiro Hiwatani and Shunya Nakane and Tomikimi Tsuji and Satoshi Ukai",

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doi = "10.1016/j.ajp.2018.11.003",

language = "英語",

volume = "39",

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T1 - A case of autoimmune autonomic ganglionopathy with prolonged delirium

AU - Uenishi, Shinya

AU - Takahashi, Shun

AU - Nakayama, Yoshiaki

AU - Hiwatani, Yasuhiro

AU - Nakane, Shunya

AU - Tsuji, Tomikimi

AU - Ukai, Satoshi

PY - 2019/1

Y1 - 2019/1

N2 - Autoimmune autonomic ganglionopathy (AAG) is a rare acquired immune-mediated disorder that leads to autonomic failure. It is sometimes complicated by mental and behavioral symptoms. We report a case of 72-year-old male with AAG who was admitted to the psychiatric department for prolonged severe delirium. Repeated loss of consciousness attributed to severe orthostatic hypotension disturbed recovery from delirium. In addition, intracerebral hemorrhage occurred during hospitalization, and this cerebrovascular event may have been substantially affected by unstable blood pressure due to AAG. This case suggests importance of differential diagnosis of AAG in patients with mental and behavioral symptoms accompanying severe autonomic failure.

AB - Autoimmune autonomic ganglionopathy (AAG) is a rare acquired immune-mediated disorder that leads to autonomic failure. It is sometimes complicated by mental and behavioral symptoms. We report a case of 72-year-old male with AAG who was admitted to the psychiatric department for prolonged severe delirium. Repeated loss of consciousness attributed to severe orthostatic hypotension disturbed recovery from delirium. In addition, intracerebral hemorrhage occurred during hospitalization, and this cerebrovascular event may have been substantially affected by unstable blood pressure due to AAG. This case suggests importance of differential diagnosis of AAG in patients with mental and behavioral symptoms accompanying severe autonomic failure.

KW - Autoimmune autonomic ganglionopathy

KW - Autonomic failure

KW - Delirium

KW - Elderly

KW - Ganglionic nicotinic acetylcholine receptor autoantibody

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U2 - 10.1016/j.ajp.2018.11.003

DO - 10.1016/j.ajp.2018.11.003

M3 - 学術論文

C2 - 30466057

AN - SCOPUS:85056712660

SN - 1876-2018

VL - 39

SP - 8

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JO - Asian Journal of Psychiatry

JF - Asian Journal of Psychiatry

ER -

A case of autoimmune autonomic ganglionopathy with prolonged delirium

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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