I型アレルギー疾患の制御にむけたFDCによるIgA抗体の産生制御機構の基礎的研究

Research output

Research output per year 2022 2023 2024 2024

• 18 Presentation
• 2 Article

Research output per year

Research output per year

Search results

• 2024

  ABCD1欠損ヒトアストロサイトーマU87細胞株のNLRP3インフラマソーム活性化機構の解析.

  守田 雅志, 松沢 紗良, 國石 （彦坂） 茉里 & 宗 孝紀., 2024.

  Research output: Contribution to conference › Presentation

• Basic characterization of TNF ligand-based agonists targeting OX40, 4-1BB, CD27, and GITR expressed by T cells.

  So, T., Nagai, H., Azuma, M., Sato, A., Suzuki, A., Ito, A., Morita, M., Hikosaka-Kuniishi, M. & Ishii., N., 2024.

  Research output: Contribution to conference › Presentation

• B細胞におけるTRAF5の高発現はTLRシグナルを介した IgM 抗体産生能の抑制に重要か？

  東充輝, 斉藤弘晃, 若泉知美, 岩谷航洋, 小澤勇介, 守田雅志, 國石（彦坂）茉里 & 宗孝紀., 2024.

  Research output: Contribution to conference › Presentation

• Functional characterization of antibody fusion-single-chain TNF proteins that agonize costimulatory TNFR expressed by T cells.

  Nagai, H., Azuma, M., Sato, A., Ogawara, S., Tsutsui, Y., Suzuki, A., Matsuyama, S., Wakaizumi, T., Morita, M., Hikosaka-Kuniishi, M., Ishii, N. & So., T., 2024.

  Research output: Contribution to conference › Presentation

• Is the regulatory activity of TRAF5 for IL-6 receptor signaling important for the differentiation of follicular helper T cells?

  Hikosaka-Kuniishi, M., Ogawara, S., Iwata, C., Wakaizumi, T., Nagai, H., Azuma, M., Morita, M., Ishii, N. & So., T., 2024.

  Research output: Contribution to conference › Presentation

• Structural and functional characterization of recombinant OX40 ligand fusion proteins.

  Sato, A., Azuma, M., Nagai, H., Ito, A., Morita, M., Hikosaka-Kuniishi, M., Ishii, N. & So., T., 2024.

  Research output: Contribution to conference › Presentation

• The expression level of TRAF5 negatively impacts the TLR signaling.

  Azuma, M., Saito, H., Wakaizumi, T., Iwatani, K., Ozawa, Y., Morita, M., Kuniishi-Hikosaka, M., Ishii, N. & So., T., 2024.

  Research output: Contribution to conference › Presentation

• T細胞に発現するTNF受容体ファミリー分子OX40の機能を制御するOX40リガンドタンパク質の構造と機能評価.

  佐藤 綾香, 東 充輝, 永井 穂高, 鈴木 綾乃, 伊藤 文, 守田 雅志, 國石（彦坂） 茉里 & 宗 孝紀., 2024.

  Research output: Contribution to conference › Presentation

• マウス粘膜組織におけるIgA産生へのTraf5の役割の検討.

  國石(彦坂)茉里, 筒井雄太, 小林奏一朗, 東充輝, 真柄弘汰, 小河原さやか, 岩田千恵梨, 若泉知美, 守田雅志 & 宗孝紀., 2024.

  Research output: Contribution to conference › Presentation
• 2023

  Elucidation of the relationship between the expression level of TRAF5 and the negative regulatory function of TRAF5 for TLR signaling.

  Azuma, M., Saito, H., Iwatani, K., Wakaizumi, T., Imai, W., Ogawara, S., Morita, M., Hikosaka-Kuniishi, M. & So., T., 2023.

  Research output: Contribution to conference › Presentation

• Enhanced Th1 response mediated by LXR activation in ABCD1-deficient CD4+ T cells.

  Morita, M., Maeda, R., Oishi, M., Nagamori, R., Kuniishi, M. & So., T., 2023.

  Research output: Contribution to conference › Presentation

• Functional evaluation of single-chain TNF ligand-Fc fusion proteins for activation of co-stimulatory TNF receptors expressed by T-lymphocytes.

  Nagai, H., Azuma, M., Sato, A., Shibui, N., Ogawara, S., Tsutsui, Y., Suzuki, A., Wakaizumi, T., Ito, A., Matsuyama, S., Morita, M., Hikosaka-Kuniishi, M. & So., T., 2023.

  Research output: Contribution to conference › Presentation

• Neural crest-derived mesenchymal cells support thymic reconstitution after lethal irradiation.

  Narki Tetteh, D., Hikosaka-Kuniishi, M. & Yamazaki, H., 2023.

  Research output: Contribution to conference › Presentation

• Structural requirement of soluble OX40 ligand protein for efficient induction of co-stimulatory signaling mediated by OX40.

  Sato, A., Azuma, M., Nagai, H., Shibui, N., Ogawara, S., Tsustui, Y., Suzuki, A., Ito, A., Wakaizumi, T., Matsuyama, S., Morita, M., Hikosaka-Kuniishi, M. & So., T., 2023.

  Research output: Contribution to conference › Presentation

• TRAF5の欠損がマウスのリンパ組織におけるTfh細胞とGC B細胞の産生に及ぼす影響.

  小河原さやか, 國石茉里, 岩田千恵梨, 若泉知美, 永井穂高, 東充輝, 真柄弘汰, 守田雅志 & 宗孝紀., 2023.

  Research output: Contribution to conference › Presentation

• TRAF5欠損B細胞のTLRシグナル応答の解析.

  若泉知美, 東充輝, 斉藤弘晃, 小澤勇介, 岩谷航洋, 守田雅志, 國石茉里 & 宗孝紀., 2023.

  Research output: Contribution to conference › Presentation

• Traf5欠損マウスの腸管粘膜固有層におけるIgA産生機構の解析

  筒井雄太, 國石茉里, 小林奏一朗, 東充輝, 真柄弘汰, 小河原さやか, 岩田千恵梨, 若泉知美, 守田雅志 & 宗孝紀., 2023.

  Research output: Contribution to conference › Presentation
• 2022

  The role of isolated CD35+ follicular dendritic cells in the differentiation from B cells to IgA+ GL7+ cells

  Hikosaka-Kuniishi, M., Yamane, T., Narki Tetteh, D. & Yamazaki, H., 2022.

  Research output: Contribution to conference › Presentation