Mechanisms of female-specific expression of drug-metabolizing enzyme CYP3A : comparison between human and mouse

Research output

Research output per year 2008 2008 2010 2011

• 10 Presentation
• 9 Article

Research output per year

Research output per year

Search results

• 2008

  Forkhead box A2-mediated regulation of female-predominant expression of the mouse Cyp2b9 gene.

  T., H., T., S., M., A., A., N., H., Y., S., I., H., T. & N., N., 2008, In: Drug Metab.Dispos. 36. p. 1080-1087

  Research output: Contribution to journal › Article › peer-review

• Glucocorticoid-mediated induction of mouse Cyp3a41 gene expression ; involvement of glucocorticoid receptor and hepatocyte nuclear factor 4 alpha

  Wattanaporn, B., 佐久間勉 & 根本信雄, 2008.

  Research output: Contribution to conference › Presentation

• Synergism of glucocorticoid hormone with growth hormone for female-specific mouse Cyp3a44 gene expression.

  T., S., W., B., T., H. & N., N., 2008, In: Drug Metab.Dispos. 36. p. 878-884

  Research output: Contribution to journal › Article › peer-review

• グルココルチコイドによるCyp3a41遺伝子の調節機構:C/EBPの役割

  Wattanaporn, B., 佐久間勉, 赤田真美 & 根本信雄, 2008.

  Research output: Contribution to conference › Presentation

• マウスCyp3a41の性特異的発現におけるHNF4αの役割

  古澤之裕, 佐久間勉, 上野真一, Wattanaporn, B., 坡下真大 & 根本信雄, 2008.

  Research output: Contribution to conference › Presentation

• メス優位に発現するマウスCyp3a41遺伝子転写過程におけるHNF4αの役割

  根本信雄, 古澤裕之, 上野真一 & 佐久間勉, 2008.

  Research output: Contribution to conference › Presentation
• 2009

  Alteration of acetaminophen-induced cytotoxicity in mouse hepatocytes during primary culture.

  A, J., A, T., S, I., Y., K., S, K., T., S. & N., N., 2009, In: J.Health Sci. 55. p. 767-776

  Research output: Contribution to journal › Article › peer-review

• Sex differences of drug-metabolizing enzyme : female predominant expression of human and mouse cytochrome P450 3A isoforms

  T, S. & al., E., 2009, In: J.Health Sci. 55. p. 325-337

  Research output: Contribution to journal › Article › peer-review

• グルココルチコイドによるCyp3a41遺伝子の発現調節機構:Glucocoeticoid receptorおよびHepatocyte nuclear factor-4αの役割

  Wattanaporn, B., 佐久間勉, 河崎優希 & 根本信雄, 2009.

  Research output: Contribution to conference › Presentation
• 2010

  Cyp3a41遺伝子メス特異的発現の調節機構

  佐久間勉, Wattanaporn, B., 河崎優希, 近藤佐千子 & 根本信雄, 2010.

  Research output: Contribution to conference › Presentation

• Gender-associated modulation of inducible CYP1A1 expression by andrographolide in mouse liver.

  K., J., S., K., W., C., T., S., Y., K. & N., N., 2010, In: Eur.J.Pharm.Sci. 39. p. 394-401

  Research output: Contribution to journal › Article › peer-review

• Potent modification of inducible CYP1A1 expression by flavonoids.

  W., C., S., K., K., J., Y., K., T., S. & N., N., 2010, In: Biol.Pharm.Bull. 33. p. 1698-1703

  Research output: Contribution to journal › Article › peer-review

• Regulatory xenobiotic responsive elements in the distal 5'-flanking region of the mouse Cypla2 gene required for transcriptional activation by 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  Y., K., T., S., Y., G. & N., N., 2010, In: Drug Metab.Dispos. 38. p. 1640-1643

  Research output: Contribution to journal › Article › peer-review

• Regulatory XREs in distal 5'-flanking region of the mouse Cypla2 gene for transcriptional activation by 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  Y., K., Goto, Y., T., S. & N., N., 2010.

  Research output: Contribution to conference › Presentation

• Role of hepatocyte nuclear factor 4 alpha and chromatin structure in the regulation of female-specific Cyp3a41 gene expression.

  T., S., W., B., Y., K. & N., N., 2010.

  Research output: Contribution to conference › Presentation

• マウスCyp3a41遺伝子構造とHNF4αによる性特異的発現

  佐久間勉, 池松怜美, Wattanaporn, B., 河崎優希 & 根本信雄, 2010.

  Research output: Contribution to conference › Presentation

• メスマウス肝でのCyp3a41遺伝子発現におけるクロマチン構造とHNF4αの役割

  佐久間勉, 池松怜美, Wattanaporn, B., 河崎優希, 近藤佐千子 & 根本信雄, 2010.

  Research output: Contribution to conference › Presentation
• 2011

  Cellular glutathione content modulates the effect of andrographolide on β-naphthoflavone-induced CYP1A1 mRNA expression in mouse hepatocytes

  S., K., W., C., A., J., T., S. & N., N., 2011, In: Toxicology 280. p. 18-23

  Research output: Contribution to journal › Article › peer-review

• Hepatocyte nuclear factor 4 alpha regulates expression of the mouse female-specific Cyp3a41 gene in the liver

  W., B., T., S., Y., K. & N, N., 2011, In: Drug Metabolism and Disposition. 39, 3, p. 490-497

  Research output: Contribution to journal › Article › peer-review