Research on the mechanism of arrhythmia induced by general anesthetic on atrial pacemaker

  • 畠山, 登 (Principal Investigator)
  • SHIBUYA, Nobuko (Co-Investigator(Kenkyū-buntansha))

Project Details

Abstract

Because sevoflurane strongly inhibited the repolarizing currents, it could affect pacemaking mechanism and it could cause arrhythmia during general anesthesia.
StatusFinished
Effective start/end date2003/01/01 → 2005/12/31

Funding

  • Japan Society for the Promotion of Science: ¥2,800,000.00

Keywords

  • ペースメーカー
  • 心筋細胞
  • 吸入麻酔薬
  • 静脈麻酔薬
  • HERGチャネル
  • 全身麻酔薬
  • 心房筋細胞
  • 不整脈
  • カリウムチャネル
  • QT時間
  • 活動電位
  • pacemaker
  • cardiac myocyte
  • inhaled anesthetic
  • intravenous anesthetic
  • HERG channel

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