Study of the molecular mechanism of synaptogenesis using withanolides, novel anti-dementia drugs

Research output

Research output per year 2005 2005 2006 2007 2008

• 37 Presentation
• 20 Article
• 8 Patent
• 2 Book
• 1 More
  • 1 Review article

Research output per year

Research output per year

Search results

• 2008

  Influence of persimmon polyphenolic oligomers on memory impairment in senescence accelerated mouse prone 8(SAMP8)

  Lee, Y.A, Cho, E.J., Tanaka, T., Tohda, C., Yokozawa & T, 2008.

  Research output: Contribution to conference › Presentation

• The effect of Wen-Pi-Tang on disease progression of amyotrophic lateral sclerosis model mice

  Sekiya, M., Tahara, Ichiyanagi, A., T., Ikeshiro, Y., Tohda, C., Yokozawa & T, 2008.

  Research output: Contribution to conference › Presentation

• The molecular mechanism of sominone which enhance neuronal network formation

  Tohda, C., Joyashiki & E, 2008.

  Research output: Contribution to conference › Presentation

• 神経回路網形成を促進するsominoneの作用機序.

  東田千尋 & 城屋敷枝里, 2008.

  Research output: Contribution to conference › Presentation

• 筋萎縮性側索硬化症モデルマウスを用いた温脾湯の検討.

  関谷倫子, 田原愛, 一柳孝司, 池城安正, 東田千尋 & 横澤隆子, 2008.

  Research output: Contribution to conference › Presentation

• 老化促進モデルマウスの記憶障害に対する柿ポリフェノールオリゴマーの影響

  李英娥, 趙恩珠, 田中隆, 東田千尋 & 横澤隆子, 2008.

  Research output: Contribution to conference › Presentation
• 2007

  Kampo formula Kihi-to improves memory disorder in Alzheimer's disease model mice by calpain inhibition

  Naito, R., Tohda, C., Yokozawa & T, 2007.

  Research output: Contribution to conference › Presentation

• Neuronの極性形成を促進させるmultiple molecular mechanismにより神経変性疾患を治療する和漢薬.

  東田千尋, 2007.

  Research output: Contribution to conference › Presentation

• PI3KノックアウトマウスのADHD様行動とミエリン化軸索の形成不全.

  中西類子, 東田千尋, 横澤隆子, 山本武 & 門脇真, 2007.

  Research output: Contribution to conference › Presentation

• The mechanism of memory improvement by Kihi-to

  Joyashiki, E., Naito, R., Tohda & C, 2007.

  Research output: Contribution to conference › Presentation

• Therapeutic potency of Kampo medicine against neurodegenerative disease by multiple molecular mechanisms of enhamcing neuronal polarity.(Symposium)

  Tohda & C, 2007.

  Research output: Contribution to conference › Presentation

• 帰脾湯によるアルツハイマー型記憶障害の改善作用におけるcalpainの関与.

  内藤理絵, 東田千尋 & 横澤隆子, 2007.

  Research output: Contribution to conference › Presentation

• 帰脾湯による記憶障害改善作用のメカニズム.

  城屋敷枝里, 内藤理絵 & 東田千尋, 2007.

  Research output: Contribution to conference › Presentation
• 2006

  ADHD-like behavior, synaptic loss and hypoplasia of myelinated axons by PI3 kinase deficiency

  Tohda, C., Nakanishi, R., Yokozawa, T., Kadowaki & M, 2006.

  Research output: Contribution to conference › Presentation

• Development of a Kampo formula for anti-dementia

  Matsuyama, S., Tohda, C., Komatsu & K, 2006.

  Research output: Contribution to conference › Presentation

• Improvement of neurodegenerative diseases by constituents of Ashwagandha

  Tohda & C, 2006.

  Research output: Contribution to conference › Presentation

• Improvement of spinal cord injury by oral administration of withanoside IV

  Nakayama, N., Tohda, C., Yokozawa & T, 2006.

  Research output: Contribution to conference › Presentation

• Improvement on spinal cord injury by oral administration of withanoside IV

  Nakayama, N., Tohda, C., Yokozawa & T, 2006.

  Research output: Contribution to conference › Presentation

• PI3KノックアウトマウスのADHD動物モデルとしての検討.

  中西類子, 東田千尋, 横澤隆子, 山本武 & 門脇真, 2006.

  Research output: Contribution to conference › Presentation

• Synaptic regeneration and memory improvement by the methanol extract of Eleutherococcus senticosus

  Tohda, C., Ichimura, M., Suetsugu, K., Komatsu & K, 2006.

  Research output: Contribution to conference › Presentation

• Wakan-yaku which improves dementia by recoveries from neuritic atrophy and synaptic loss-Behaviors, Tissues, Molecular mechanisms

  Tohda & C, 2006.

  Research output: Contribution to conference › Presentation

• Withanoside IVの経口投与による脊髄損傷改善作用

  中山なつき, 東田千尋 & 横澤隆子, 2006.

  Research output: Contribution to conference › Presentation

• アシュバガンダ成分による神経変性疾患の改善作用.

  東田千尋, 2006.

  Research output: Contribution to conference › Presentation

• 刺五加メタノールエキスによるシナプス再形成作用と記憶障害改善作用.

  東田千尋, 市村真帆子, 末次一博 & 小松かつ子, 2006.

  Research output: Contribution to conference › Presentation

• 帰脾湯によるアルツハイマー型記憶障害の改善作用

  内藤理絵, 東田千尋 & 横澤隆子, 2006.

  Research output: Contribution to conference › Presentation

• 慢性腎不全ラットにおけるγ-Aminobutyric acid(GABA)の役割の検討.

  佐々木澄代, 東田千尋, 大和田滋 & 横澤隆子, 2006.

  Research output: Contribution to conference › Presentation

• 神経突起の萎縮とシナプス減少の回復により認知症改善作用を示す和漢薬-行動、組織、分子機序.

  東田千尋, 2006.

  Research output: Contribution to conference › Presentation

• 軸索およびシナプス形成の促進による神経変性疾患の克服-治療薬開発と病態機序の解明に向けて-.(Overcoming several neurodegenerative diseases by axonal and synaptic formations-the development of therapeutic medicines and unraveling pathophysiological mechanisms-)

  C., T., 2006.

  Research output: Contribution to conference › Presentation
• 2005

  ADHD-like behavior, synaptic loss and hypoplasia of myelinated axons by PI3 kinase deficiency.

  C., T., R., N. & T. and Kadowaki M., Y., 2005.

  Research output: Contribution to conference › Presentation

• Evaluation of Amula using aged rats

  Kim, H., Satoh, Tohda, A., C., Okubo, T., Junesia, L.R., Yokozawa & T, 2005.

  Research output: Contribution to conference › Presentation

• Improvement on spinal cord injury by oral administration of withanoside IV.

  N., N. & C. and Yokozawa T., T., 2005.

  Research output: Contribution to conference › Presentation

• Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 followed by PI3-kinase cascade.

  中西類子, 東田千尋, 橋本斎, 小松かつ子 & 横澤隆子, 2005.

  Research output: Contribution to conference › Presentation

• Recovery from memory disorder by Kampo formula Kihi-to in Alzheimer's disease model mice.

  NaitoR. & C. and Yokozawa T., T., 2005.

  Research output: Contribution to conference › Presentation

• Restoration from neurodegenerative changes by withanolide IV and by its active metabolite, sominone

  久保山友晴, 東田千尋 & 小松かつ子, 2005.

  Research output: Contribution to conference › Presentation

• Synaptic reconstruction effect of natural medicines; identifying new anti-dementia drugs and analyzing the molecular mechanism of synaptogenesis. 2005/11/23-25(Toyama)

  C, T., 2005.

  Research output: Contribution to conference › Presentation

• 加齢ラットを用いたアムラの評価.

  金賢柱, 佐藤亜希子, 東田千尋, 大久保勉, L.R.ジュネジャ & 横澤隆子, 2005.

  Research output: Contribution to conference › Presentation

• 認知症に有効な漢方処方の開発.

  松山修二, 東田千尋 & 小松かつ子, 2005.

  Research output: Contribution to conference › Presentation