Research output per year
Research output per year
Project Details
Abstract
In atrial myocytes from septic model of guinea pig, duration of action potential was significantly shortened. This may be the result of the nitration of the ion channels that would alter channel functions rather than the changes in atrial expression of the channels. The reduction of action potential duration could play a role for the development of atrial tachyarrhythmia in sepsis.
| Status | Finished |
|---|---|
| Effective start/end date | 2009/01/01 → 2011/12/31 |
Funding
- Japan Society for the Promotion of Science: ¥4,420,000.00
Keywords
- 敗血症
- 不整脈
- イオンチャネル
- 全身性炎症反応症候群
- 心筋
- 活動電位
- チャネル発現
- カルシウムチャネル
- カリウムチャネル
- 全身性炎症症候群
- 頻脈性不整脈
- ショック
- 心房筋
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Role of ion channels in sepsis-induced atrial tachyarrhythmias in guinea pigs
Aoki, Y., Hatakeyama, N., Yamamoto, S., Kinoshita, H., Matsuda, N., Hattori, Y. & Yamazaki, M., 2012/05, In: British Journal of Pharmacology. 166, 1, p. 390-400 11 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Modulation of Potassium Channel Plays a Role for Septic Tachyarrhythmia
N., H., 2011.Research output: Contribution to conference › Presentation
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Modulation of Potassium Channel Plays a Role for Septic Tachyarrhythmia
Hatakeyama, N., 2011.Research output: Contribution to conference › Presentation