Research output per year
Research output per year
Project Details
Abstract
Evaluation of the relationship between pharmacological effect and blood concentration of the drug and investigation of the mechanisms for interindividual variability of the pharmacokinetics of the drug are needed to optimize the drug therapy for patients. Recently, we have clarified that the 3 step analysis is useful method to analyze the limited number of patients and/or data in the exploratory clinical trials. In the present study, we verified whether 3 step data analysis is useful to evaluate the pharmacokinetics of the drug in small or medium scale clinical trials
| Status | Finished |
|---|---|
| Effective start/end date | 2009/01/01 → 2011/12/31 |
Funding
- Japan Society for the Promotion of Science: ¥4,550,000.00
Keywords
- 採血デザイン
- 臨床薬物動態試験
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Population pharmacokinetics of mizoribine in pediatric recipients of renal transplantation
Ishida, K., Motoyama, O., Shishido, S., Tsuzuki, K. & Hashimoto, Y., 2012/10, In: Clinical and Experimental Nephrology. 16, 5, p. 799-804 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Effect of genetic polymorphisms of nucleoside and efflux transporters on bioavailability of mizoribine
M., F., K., I., M., T., H., M., T., M. & Hashimoto Y., A., 2011.Research output: Contribution to conference › Presentation
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Effect of genetic polymorphisms of nucleoside and efflux transporters on bioavailability of mizoribine in healthy Japanese males
Fukao, M., 2011.Research output: Contribution to conference › Presentation