Using oral squamous cancer cell lines, over-expression of MMP9 or periostin was strongly observed in high invasive cell line (HSC4) compared with low invasive cell line (HSC3). Apoptosis was induced in HSC4 cells with low dose bisphosphonate. Moreover, induction of apoptosis in cell line was enhanced by addition to Ca.
Status
Finished
Effective start/end date
2008/01/01 → 2010/12/31
Funding
Japan Society for the Promotion of Science: ¥4,550,000.00
Yamazaki, T., Sabit, H., Oya, T., Ishii, Y., Hamashima, T., Tokunaga, A., Ishizawa, S., Jie, S., Kurashige, Y., Matsushima, T., Furuta, I., Noguchi, M. & Sasahara, M., 2009/09, In: Journal of the Peripheral Nervous System.14, 3, p. 165-17612 p.
Research output: Contribution to journal › Article › peer-review