Sperm factor caused a transient increase in intracellular calcium concentration of sea urchin eggs.

  • 黒田, 英世 (Principal Investigator)
  • 菊地, 徹 (Co-Investigator(Kenkyū-buntansha))

Project Details

Abstract

The Ca^<2+>-transient by sperm extract was inhibited by heparine or GDP-betaS unlike one during fertilization. Furthermore, sperm extract caused a transient increase in IP_3 mass but not in cGMP mass. These results show that sperm extract caused IICR in fertilized eggs but not stimulate CICR.
StatusFinished
Effective start/end date1993/01/01 → 1994/12/31

Funding

  • Japan Society for the Promotion of Science: ¥2,100,000.00

Keywords

  • ウニ
  • 卵細胞
  • カルシウムイオン
  • 精子
  • Inositol-1,4,5-trisphoshate
  • CGMP
  • Inositol 1,4,5-Trisphosphate
  • cGMP
  • sea urchin
  • egg
  • calcium ion
  • sperm
  • inositol 1,4,5-trisphosphate

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