A neuropsychological study for resolution of pathology in the prefrontal dysfunction

It aimed at clarifying the neural base of pathology of prefrontal dysfunction centering on schizophrenia and the role of prefrontal function. This study suggests failure to use a semanticorganization strategy for memory in schizophrenia might be related to reduced volume in the inferior frontal gyrus. The difference of function between dorso-lateral and medial prefrontal area became more clear from memory function or control function using functional neuroimaging. Although patients with frontal lobe damage showed worse performance in neuropsychological tests, it was suggested that the functions to fall by damaged area differ.