Analysis of peroxisome membrane biogenesis and application for Nano-medicine

Research output

Research output per year 2011 2011 2012 2013 2014

• 41 Presentation
• 5 Article
• 1 Chapter
• 1 Review article

Research output per year

Research output per year

Search results

• 2014

  ABCトランスポーターABCD4のリソソームへの局在化メカニズムの解析．

  岡元拓海, 川口甲介, 守田雅志 & 今中常雄．, 2014.

  Research output: Contribution to conference › Presentation

• New insight into ABC protein subfamily D : Substrate transport of ABCD1 and targeting of ABCD4 to lysosome

  T, I., 2014.

  Research output: Contribution to conference › Presentation

• New insight into ABC protein subfamily D: Substrate transport of ABCD1 and targeting of ABCD4 to lysosome.

  T., I., 2014.

  Research output: Contribution to conference › Presentation

• Subcellular localization of ABC transporter ABCD4 is regulated by a lysosomal membrane protein, LMBD1. 5th FEBS Special Meeting on ABC Protein.

  K, K., T, O., M, M. & T., I., 2014.

  Research output: Contribution to conference › Presentation

• ミスセンス変異ABCD1タンパク質を安定化する副腎白質ジストロフィー候補治療薬の探索．

  守田雅志, DG, K., 山崎こず枝, 佐藤愛里, 下澤伸行 & 今中常雄, 2014.

  Research output: Contribution to conference › Presentation

• メタノール資化性酵母を用いたヒトABCトランスポーターABCD1の発現と機能解析．

  池島俊李, 川口甲介, 山田純司, 守田雅志 & 今中常雄, 2014.

  Research output: Contribution to conference › Presentation
• 2013

  ABCD1欠損マウスの分子病態の解析とロレンツ油の効果．

  守田雅志, 小林晃, 松本隼, 渡辺志朗, 下澤伸行 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• ABCDタンパク質のオルガネラ局在化におけるN末端疎水性モチーフの役割：種を超えた共通性．

  李朝香, 朝日彰子, 川口甲介, 守田雅志 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• ABCトランスポーターABCD４のリソソームへの局在化におけるLMBD1の役割．

  岡元拓海, 川口甲介, 金林峰 & 守田雅志, 2013.

  Research output: Contribution to conference › Presentation

• A new therapeutic approach for trypanosome protozoa : Screening of chemical compounds that inhibit biogenesis of glycosome

  Y., W., N., O., K., K., M., M., Y., K. & Imanaka T, A., 2013.

  Research output: Contribution to conference › Presentation

• A new therapeutic approach for trypanosome protozoa: Screening of chemical compounds that inhibit biogenesis of glycosome.

  Y, W., N, O., K, K., M, M., Y, K. & T., I., 2013.

  Research output: Contribution to conference › Presentation

• A novel double mutation in the ABCD1 gene in a patient with x-linked adrenoleukodystrophy: Analysis of the stability and function of the mutant ABCD1 protein

  Morita, M., Kobayashi, J., Yamazaki, K., Kawaguchi, K., Honda, A., Sugai, K., Shimozawa, N., Koide, R. & Imanaka, T., 2013, JIMD Reports. Springer, p. 95-102 8 p. (JIMD Reports; vol. 10).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  Open Access

  • X-linked 100%
  • ABCD1 100%
  • Double mutation 100%
  • Adrenoleukodystrophy 100%
  • ABCD1 Gene 100%
  13 Scopus citations

• Establishment and application of fluorescence-based assay for screening of chemical compounds that stabilize mutant ABCD1 protein responsible for adrenoleukodystrophy.

  DG, K., M, M., K, Y., K, A., N, S. & T., I., 2013.

  Research output: Contribution to conference › Presentation

• Molecular species of phospholipids with very long chain fatty acids in skin fibroblasts of Zellweger syndrome

  Hama, K., Nagai, T., Nishizawa, C., Ikeda, K., Morita, M., Satoh, N., Nakanishi, H., Imanaka, T., Shimozawa, N., Taguchi, R., Inoue, K. & Yokoyama, K., 2013/12, In: Lipids. 48, 12, p. 1253-1267 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipids 100%
  • Long-chain Polyunsaturated Fatty Acids (LC-PUFA) 100%
  • Skin Fibroblasts 100%
  • Zellweger Syndrome 100%
  • Molecular Species 100%
  18 Scopus citations

• Screening of chemical compounds that stabilize ABCD1 protein with missense mutation.

  M, M., DG, K., K, Y., K, A., N, S. & T., I., 2013.

  Research output: Contribution to conference › Presentation

• Subcellular localization of ABC transporter ABCD4 is regulated by LMBD1

  T, O., K, K., M, M. & T., I., 2013.

  Research output: Contribution to conference › Presentation

• グリコソーム形成因子をターゲットとした新規抗トリパノソーマ薬の開発．

  渡邊雄一, 奥山尚輝, 川口甲介, 守田雅志, 柏山恭範 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• ペルオキシソーム膜ABCタンパク質ABCD1の機能解析.

  池島俊季, 川口甲介, 守田雅志 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• ペルオキシソーム膜形成因子Pex3pと相互作用するタンパク質の検索

  高﨑満喜子, 渡邊雄一, 深澤力也, 川口甲介, 守田雅志, 大熊芳明 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• ペルオキシソーム膜形成因子Pex3pと相互作用するタンパク質の検索．

  高﨑満喜子, 渡邊雄一, 深澤力也, 川口甲介, 守田雅志, 大熊芳明 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• メタノール資化性酵母を用いたペルオキシソーム膜ABCタンパク質ABCD1の 発現と機能解析．

  池島俊季, 川口甲介, 守田雅志 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• メタノール資化性酵母を用いたペルオキシソーム膜ABCタンパク質の発現と機能解析．

  池島俊李, 山口甲介, 守田雅志 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• 副腎白質ジストロフィーの治療薬開発：ABCD1タンパク質の安定化を指標としたスクリーニング系の構築．

  有村洸平, 守田雅志, DG, K., 山崎こず枝, 下澤伸行 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• 副腎白質ジストロフィー：レンチウイルスベクターを用いたABCD1遺伝子発現と骨髄移植．

  松本隼, 守田雅志, 渡邊康春, 長井良憲, 小林博司, 高津聖志 & 今中常雄, 2013.

  Research output: Contribution to conference › Presentation

• 極長鎖脂肪酸含有脂質の定量解析による２つのペルオキシソーム病の比較．

  西澤千穂, 濱弘太郎, 永井徹, 池田和貴, 守田雅志, 唐澤健, 原田史子, 谷川和也, 佐藤典子, 田口良．下澤伸行．今中常雄, 井上圭三 & 横山和明, 2013.

  Research output: Contribution to conference › Presentation
• 2012

  A novel double mutation in ABCD1 gene in a patient with X-linked adrenoleukodystrophy: Analysis of the stability and function of the mutant ABCD1 protein.

  M., M., K., Y., K., K., N., S., R., K. & Imanaka T, A., 2012.

  Research output: Contribution to conference › Presentation

• A screening system to discover chemical compounds that stabilize ABCD1 protein with missense mutation.

  M., M., D. G., K., K., Y., N., S. & Imanaka T., A., 2012.

  Research output: Contribution to conference › Presentation

• A screening system to discover chemical compounds that stabilize missense mutant ABCD1 protein.

  M., M., D. G., K., K., Y., K., A., N., S. & Imanaka T., A., 2012.

  Research output: Contribution to conference › Presentation

• Establishment of screening system to discover candidates of chemical chaperone that stabilize mutant ABCD1 responsible for adrenoleukodystrophy.

  D. G., K., A., L., K., Y., K., K., M., M. & Imanaka T., A., 2012.

  Research output: Contribution to conference › Presentation

• Peroxisomal ABC transporters: Structure, function and role in disease

  Morita, M. & Imanaka, T., 2012/09, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1822, 9, p. 1387-1396 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • ATP-binding Cassette Transporter A1 (ABCA1) 100%
  • Peroxisomal 100%
  • Transport Structure 100%
  • ABC Transporter 100%
  • ATP-binding Cassette Transporter 100%
  149 Scopus citations

• Very long chain fatty acidβ-oxidation in astrocytes : Contribution of the ABCD1-dependent and -independent pathways

  M., M., S., S., A., A. & Imanaka T, A., 2012, In: Biol. Pharm. Bull.. 35, p. 1972-1979

  Research output: Contribution to journal › Article › peer-review

• Very long chain fatty acid β-oxidation in astrocytes: Contribution of the ABCD1-dependent and -independent pathways.

  M., M., S., S., A., A. & Imanaka T., A., 2012, In: Biol. Pharm. Bull.. 35, p. 1972-1979

  Research output: Contribution to journal › Article › peer-review

• グリコソーム形成因子をターゲットとした原虫感染症治療薬開発のためのスクリーニング系の構築

  渡邉雄一, 奥山尚輝, 楠本梨賀, 川口甲介, 守田雅志, 柏山恭範 & 今中常雄, 2012.

  Research output: Contribution to conference › Presentation

• グリコソーム形成因子をターゲットとした原虫感染症治療薬開発のためのスクリーニング系の構築．

  渡邉雄一, 奥山尚輝, 楠本梨賀, 川口甲介, 守田雅志, 柏山恭範 & 今中常雄, 2012.

  Research output: Contribution to conference › Presentation

• ペルオキシソームの多様性と動態から見た微生物の生存戦略．

  川口甲介 & 今中常雄, 2012, In: 生化学. 84, p. 840-844

  Research output: Contribution to journal › Article › peer-review

• ペルオキシソーム膜ABCタンパク質ABCD1の構造と機能．

  池島俊季, 川口甲介, 守田雅志 & 今中常雄, 2012.

  Research output: Contribution to conference › Presentation

• メタノール資化性酵母Pichia pastoris発現系を用いたABCタンパク質サブファミリーDの発現系の構築．

  池島俊季, 川口甲介, 赤池宗輔, 守田雅志 & 今中常雄, 2012.

  Research output: Contribution to conference › Presentation

• 副腎白質ジストロフィー患者の新規ABCD1遺伝子変異 -二カ所にミスセンス変異をもつABCD1 タンパク質の発現解析-．

  山崎こず枝, 守田雅志, 小出玲爾, 下澤伸行 & 今中常雄, 2012.

  Research output: Contribution to conference › Presentation
• 2011

  ABCD1 欠損マウス脳由来初代培養アストロサイトの極長鎖脂肪酸代謝と遺伝発現解析．

  谷口範壮, 新保沙織, 守田雅志 & 今中常雄, 2011.

  Research output: Contribution to conference › Presentation

• ABC subfamily d proteins and very long chain fatty acid metabolism as novel targets in adrenoleukodystrophy

  Morita, M., Shimozawa, N., Kashiwayama, Y., Suzuki, Y. & Imanaka, T., 2011, In: Current Drug Targets. 12, 5, p. 694-706 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Long-chain Polyunsaturated Fatty Acids (LC-PUFA) 100%
  • Fatty Acid Metabolism 100%
  • Adrenoleukodystrophy 100%
  • Very Long Chain Fatty Acid 100%
  • ABCD1 80%
  27 Scopus citations

• ABCタンパク質サブファミリーDのオルガネラ膜への選別輸送機構：N末端マルチオルガネラ移行シグナルの解析．

  李朝香, 朝日彰子, 阪口雅郎, 柏山恭範 & 今中常雄, 2011.

  Research output: Contribution to conference › Presentation

• ABCタンパク質サブファミリーDの細胞内局在化機構―ヒト，線虫及び粘菌での共通性―

  李朝香, 朝日彰子, 赤池宗輔, 柏山恭範, 守田雅志, 安川洋生 & 今中常雄, 2011.

  Research output: Contribution to conference › Presentation

• Complex formation of ABC protein, P70R/ABCD4 on endoplasmic reticulum membranes.

  T., U., Y., K. & Imanaka T., A., 2011.

  Research output: Contribution to conference › Presentation

• Identification of a substrate-binding site in a peroxisomal β-oxidation enzyme by diazirine-based photoaffinity labeling.

  T., T., Y, K., T, I. & Hatanaka Y., A., 2011.

  Research output: Contribution to conference › Presentation

• Very long chain fatty acid β-oxidation in astrocytic cells; contribution of ABCD1-dependent and -independent pathways.

  M., M., S., S., A., A. & Imanaka T., A., 2011.

  Research output: Contribution to conference › Presentation

• 小胞体膜上に存在するABCタンパク質P70R(ABCD4)の存在状態の解析.

  上杉泰介, 柏山恭範 & 今中常雄, 2011.

  Research output: Contribution to conference › Presentation

• 小胞体膜上に存在するABCタンパク質P70R (ABCD4) の存在状態の解析．

  上杉泰介, 柏山恭範 & 今中常雄, 2011.

  Research output: Contribution to conference › Presentation

• 小胞体膜上に局在するABCD4 (P70R) の存在様式と機能．

  上杉泰介, 赤池宗輔, 柏山恭範, 守田雅志, 加藤博章 & 今中常雄, 2011.

  Research output: Contribution to conference › Presentation