Synthetic studies on natural products containing highly substituted heterocyclic skeletons using ring-opening cyclization of spirocyclopropanes

Nambu, Hisanori (Principal Investigator)

Synthetic and Biomolecular Organic Chemistry

4 Article
1 Review article

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2017
An Efficient Route to Highly Substituted Indoles via Tetrahydroindol-4(5H)-one Intermediates Produced by Ring-Opening Cyclization of Spirocyclopropanes with Amines
Nambu, H., Hirota, W., Fukumoto, M., Tamura, T. & Yakura, T., 2017/11/27, In: Chemistry - A European Journal. 23, 66, p. 16799-16805 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
22 Scopus citations
2016
Acid-Catalyzed Ring-Opening Cyclization of Spirocyclopropanes for the Construction of a 2-Arylbenzofuran Skeleton: Total Synthesis of Cuspidan B
Nambu, H., Ono, N. & Yakura, T., 2016/06/16, In: Synthesis. 48, 12, p. 1892-1901 10 p., ss-2016-c0077-op.
Research output: Contribution to journal › Article › peer-review
23 Scopus citations
An efficient method for the synthesis of 2′,3′-nonsubstituted cycloalkane-1,3-dione-2-spirocyclopropanes using (2-bromoethyl)-diphenylsulfonium trifluoromethanesulfonate
Nambu, H., Ono, N., Hirota, W., Fukumoto, M. & Yakura, T., 2016, In: Chemical and Pharmaceutical Bulletin. 64, 12, p. 1763-1768 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
22 Scopus citations
2015
An efficient synthesis of cycloalkane-1,3-dione-2-spirocyclopropanes from 1,3-cycloalkanediones using (1-aryl-2-bromoethyl)-dimethylsulfonium bromides: Application to a one-pot synthesis of tetrahydroindol-4(5H)-one
Nambu, H., Fukumoto, M., Hirota, W., Ono, N. & Yakura, T., 2015/06/14, In: Tetrahedron Letters. 56, 29, p. 4312-4315 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
30 Scopus citations