Keyphrases
Pharmacokinetics
67%
Carvedilol
57%
Japanese Patients
43%
Metoprolol
34%
Pharmacokinetic Variability
33%
LS180 Cell
31%
Intestinal Absorption
30%
Oral Clearance
29%
Bisoprolol
29%
Intestinal Epithelial Cells
28%
Caco-2 Cells
27%
CYP2D6*10
23%
Tadalafil
22%
Glucuronidation
20%
Plasma Concentration
20%
NONMEM
20%
Warfarin
20%
Bosentan
19%
Metabolism
18%
P-glycoprotein (P-gp)
18%
Sildenafil
17%
Mizoribine
17%
Sampling Design
17%
Ureter
17%
Human Liver Microsomes
17%
Japanese Workers
17%
Ligation
16%
Cytochrome P450 2D6 (CYP2D6)
16%
Carvedilol Enantiomers
15%
Genotype
15%
Quinidine
14%
Old Japanese
13%
Inter-individual Variability
12%
Vitamin K Epoxide Reductase
12%
Renal Failure
12%
Transcellular Transport
12%
Cytochrome P450 3A4 (CYP3A4)
11%
Na +
11%
Absorption Rate
11%
Repeated Dose
11%
Stereoselective Metabolism
11%
α-Naphthoflavone
11%
Hepatic Extraction
11%
Japanese children
11%
Amiodarone
11%
Membrane Transport Mechanism
11%
Levofloxacin
11%
Rat Intestine
11%
Dose-response Relationship
11%
Systemic Clearance
11%
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacokinetics
100%
Carvedilol
51%
Metoprolol
34%
CYP2D6
33%
Bisoprolol
29%
Bioavailability
24%
Tadalafil
22%
Warfarin
20%
P-Glycoprotein
18%
Sildenafil
17%
Congestive Heart Failure
16%
Elimination
14%
Bosentan
13%
Quinidine
13%
Kidney Failure
12%
Transcellular Transport
12%
Transcytosis
12%
Mizoribine
11%
Sodium Ion
11%
Cytochrome P450
11%
Dose-Response Relationship
11%
Levofloxacin
11%
Amiodarone
11%
Acute Kidney Failure
11%
CYP3A4
11%
CYP2C19
9%
Messenger RNA
9%
Pulmonary Hypertension
9%
Cytochrome P450 3A5
8%
Drug Concentration
7%
CYP2C9
7%
Renal Excretion
7%
Reduced Nicotinamide Adenine Dinucleotide Phosphate
7%
Anticoagulant Agent
6%
Volume of Distribution
6%
Vitamin K Epoxide Reductase
6%
Propranolol
6%
CYP3A
6%
Procainamide
6%
Ribavirin
6%
Protein Binding
6%
Tetrylammonium
5%
Bepridil
5%
Heart Arrhythmia
5%
Pharmacodynamics
5%
Maintenance Dose
5%
Flecainide
5%
Proton Pump
5%
Phenthoate
5%
Therapeutic Effect
5%
