Chemical Biology

Activities

Activities per year 2005 2012 2013 2015 2016 2018 2025

• 123 Oral presentation
• 1 Other reseach activity

Activities per year

Search results

• チオフェン共役型色素を封止したロタキサン型色素による近赤外円偏光発光

  Nishioki, K. (Speaker), Iwamura, M. (Speaker), Ohishi, Y. (Speaker), Yokoyama, S. (Speaker), Yamashita, J. (Speaker), Nozaki, K. (Speaker), Chiba, J. (Speaker) & Inouye, M. (Speaker)

  2025/03/26 → 2025/03/29

  Activity: Talk or presentation › Oral presentation

• 光線力学療法用光増感剤を指向した水溶性、安定性、膜透過性の優れたロタキサン型ポルフィリン色素

  Ichikawa, T. (Speaker), Ohishi, Y. (Speaker), Yokoyama, S. (Speaker), Iwamura, M. (Speaker), Yamashita, J. (Speaker), Nozaki, K. (Speaker), Zhu, S. (Speaker), Chiba, J. (Speaker) & Inouye, M. (Speaker)

  2025/03/26 → 2025/03/29

  Activity: Talk or presentation › Oral presentation

• アジド導入ペプチドを用いた新規クリック反応の開発

  Chiba, J. (Speaker)

  2019/11/17

  Activity: Talk or presentation › Oral presentation

• 脂肪酸代謝関連酵素プロファイリングを目的とした光ラベル法の開発

  Chiba, J. (Speaker)

  2019/11/17

  Activity: Talk or presentation › Oral presentation

• 桂皮酸型光クロスリンカーを用いた細胞膜タンパク質の光ラベル解析

  Chiba, J. (Speaker)

  2019/07/19 → 2019/07/20

  Activity: Talk or presentation › Oral presentation

• シクロデキストリンで分子封止された蛍光色素の光化学

  Ohishi, Y. (Speaker)

  2019/06/14 → 2019/06/15

  Activity: Talk or presentation › Oral presentation

• BINOL 構造を含むキラルなピリジンーアセチレンーフェノール大環状分子による天然糖の不斉識別

  Ohishi, Y. (Speaker)

  2019/06/01

  Activity: Talk or presentation › Oral presentation

• 新規経皮酸型光反応基の開発と機能評価

  Chiba, J. (Speaker)

  2019/03/20 → 2019/03/23

  Activity: Talk or presentation › Oral presentation

• クマリンに変換する新規光クロスリンカーの開発と応用

  Chiba, J. (Speaker)

  2019/03/20 → 2019/03/23

  Activity: Talk or presentation › Oral presentation

• アシルスルホンアミド型光反応基による標的タンパク質解析の効率化

  Chiba, J. (Speaker)

  2018/11/18

  Activity: Talk or presentation › Oral presentation

• 新規桂皮酸型ジアジリン光クロスリンカーの開発と機能評価

  Chiba, J. (Speaker)

  2018/11/18

  Activity: Talk or presentation › Oral presentation

• 抗HIV-1 活性を有する APOBEC の相互作用部位からなる架橋ヘリカルペプチドの開発－抗 HIV ペプチドの創薬を目指して－

  Chiba, J. (Speaker)

  2018/09/13 → 2018/09/14

  Activity: Talk or presentation › Oral presentation

• Gluconoamidinylsulfone as a new promising anitidiabetic agent: a comprehensive study based on the click-type reaction of thioamide and sulfonyl azide

  Chiba, J. (Speaker)

  2018/09/10 → 2018/09/12

  Activity: Talk or presentation › Oral presentation

• Development of crosslinked helical peptides that binds to a Vif-containing E3-ligase complex with remarkable affinity

  Chiba, J. (Speaker)

  2018/09/10 → 2018/09/12

  Activity: Talk or presentation › Oral presentation

• Improvement of target protein analysis with a photoprobe possessing N-acylsulfonamide as a cleavable linkage

  Chiba, J. (Speaker)

  2018/09/10 → 2018/09/12

  Activity: Talk or presentation › Oral presentation

• Structural analysis of allosteric domain based on multiple labeled sites using fluorogenic photocross-linker

  Chiba, J. (Speaker)

  2018/09/10 → 2018/09/12

  Activity: Talk or presentation › Oral presentation

• 酵素作用点にアルキニル C-ヌクレオチドを導入した DNA の酵素的リン酸化および酵素的連結

  Chiba, J. (Speaker)

  2018/09/09 → 2018/09/11

  Activity: Talk or presentation › Oral presentation

• 代謝プロセスを利用した脂質メディエーターの光プローブ化

  Chiba, J. (Speaker)

  2018/07/20 → 2018/07/21

  Activity: Talk or presentation › Oral presentation

• アシルスルホンアミド型光反応基によるラベルタンパク質解析の効率化

  Chiba, J. (Speaker)

  2018/03/25 → 2018/03/28

  Activity: Talk or presentation › Oral presentation

• アミノピリジン誘導体をアデニン類似体とする新規アルキニル C-ヌクレオチドの設計および合成

  Chiba, J. (Speaker)

  2018/03/20 → 2018/03/23

  Activity: Talk or presentation › Oral presentation

• Kinetic Analysis of Single Nucleotide insertion with Alkynyl C-Nucleotide Triphosphates by DNA Polymerase

  Chiba, J. (Speaker)

  2018/01/20 → 2018/01/21

  Activity: Talk or presentation › Oral presentation

• Enzymatic ligation and structural redesign of alkynyl C-nucleotides by T4 DNA Ligase

  Chiba, J. (Speaker)

  2018/01/20 → 2018/01/21

  Activity: Talk or presentation › Oral presentation

• Distance Dependence of the Electron-Transfer Rate of Electrode-Bound Duplex DNAs Modified with a Distal Redox Unit

  Chiba, J. (Speaker)

  2018/01/20 → 2018/01/21

  Activity: Talk or presentation › Oral presentation

• PAL-based fluorogenic tagging for structural analysis of ligand binding state within target protein

  Chiba, J. (Speaker)

  2017/09/19 → 2017/09/20

  Activity: Talk or presentation › Oral presentation

• スルホクリック反応を利用した光反応性プローブの簡便合成と標的タンパク質同定の効率化

  Chiba, J. (Speaker)

  2017/07/26 → 2017/07/28

  Activity: Talk or presentation › Oral presentation

• 標的タンパク質同定を目的とする切断性光蛍光ラベル法の開 発

  Chiba, J. (Speaker)

  2017/07/21 → 2017/07/22

  Activity: Talk or presentation › Oral presentation

• 発蛍光性光アフィニティーラベル法を用いたATP結合構造解析

  Chiba, J. (Speaker)

  2017/06/07 → 2017/06/09

  Activity: Talk or presentation › Oral presentation

• クリック反応を利用した光反応性プローブ作製の簡 便化と標的光蛍光ラベルへの応用

  Chiba, J. (Speaker)

  2017/03/24 → 2017/03/27

  Activity: Talk or presentation › Oral presentation

• 光切断性クマリン型光クロスリンカーを用いた標的 タンパク質同定戦略

  Chiba, J. (Speaker)

  2017/03/24 → 2017/03/27

  Activity: Talk or presentation › Oral presentation

• ポリメラーゼ伸長反応における相補性の向上を目指した アルキニル C-ヌクレオチドの構造改良

  Chiba, J. (Speaker)

  2017/03/16 → 2017/03/19

  Activity: Talk or presentation › Oral presentation

• アルキニルヌクレオチドからなる人工DNAの創出と核酸関連酵素反応への展開

  Chiba, J. (Speaker)

  2017/03/16 → 2017/03/19

  Activity: Talk or presentation › Oral presentation

• 電気化学活性 DNA における電極上でのハイブリダイゼーション 前後での電荷移動モードの変化

  Chiba, J. (Speaker)

  2017/03/16 → 2017/03/19

  Activity: Talk or presentation › Oral presentation

• Chemically Redesigned Alkynyl C-Nucleosides with Improved Performance to T4 DNA Ligase

  Chiba, J. (Speaker)

  2017/01/21 → 2017/01/22

  Activity: Talk or presentation › Oral presentation

• 触媒不要の新規なクリック型の化学反応に用いる試薬類

  Chiba, J. (Speaker)

  2016/09/30

  Activity: Talk or presentation › Oral presentation

• DNA replication using artificial C-nucleotide triphosphates with nonnatural nucleobases by Klenow fragment

  Chiba, J. (Speaker)

  2016/09/12 → 2016/09/13

  Activity: Talk or presentation › Oral presentation

• PeT-based photochemical fluorophore labeling for target identification

  Chiba, J. (Speaker)

  2016/09/12 → 2016/09/13

  Activity: Talk or presentation › Oral presentation

• A novel coupling reaction between thioamides and sulfonyl azides

  Chiba, J. (Speaker)

  2016/09/12 → 2016/09/13

  Activity: Talk or presentation › Oral presentation

• Novel Click−type Coupling Reaction of Thioamides with Sulfonyl Azides: Scope, Mechanism and Application

  Chiba, J. (Speaker)

  2016/09/12 → 2016/09/13

  Activity: Talk or presentation › Oral presentation

• アルキニル C-ヌクレオチド三リン酸を用いた酵素的 DNA 複製における一塩基伸長反応の速度論評価

  Chiba, J. (Speaker)

  2016/09/07 → 2016/09/09

  Activity: Talk or presentation › Oral presentation

• 発蛍光性光ラベルのための小分子ユニットの開発

  Chiba, J. (Speaker)

  2016/07/22 → 2016/07/23

  Activity: Talk or presentation › Oral presentation

• PeT を利用した光アフィニティー蛍光ラベル法の開発

  Chiba, J. (Speaker)

  2016/06/15 → 2016/06/17

  Activity: Talk or presentation › Oral presentation

• チオアミドとスルホニルアジドのクリック型反応を利用したノイラミニダーゼ阻害剤の標的誘導型合成

  Chiba, J. (Speaker)

  2016/06/15 → 2016/06/17

  Activity: Talk or presentation › Oral presentation

• オリゴDNAを親水性基とした両親媒性分子で構築したベシクル様ナノ構造体の表面機能化

  Chiba, J. (Speaker)

  2016/03/26 → 2016/03/29

  Activity: Talk or presentation › Oral presentation

• チオアミドとスルホニルアジドを用いる新規クリック型反応

  Chiba, J. (Speaker)

  2016/03/26 → 2016/03/29

  Activity: Talk or presentation › Oral presentation

• アルキニル C-ヌクレオチド三リン酸体を基質として用いた DNA のポリメラーゼ伸長

  Chiba, J. (Speaker)

  2016/03/24 → 2016/03/27

  Activity: Talk or presentation › Oral presentation

• 電極固定フェロセン修飾 DNA 二重鎖における鎖長と電荷移動速度との相関

  Chiba, J. (Speaker)

  2016/03/24 → 2016/03/27

  Activity: Talk or presentation › Oral presentation

• A tightly hybridizable, DNA-like architecture as a sequence-selective assembly in water

  Chiba, J. (Speaker)

  2015/11/22 → 2015/11/23

  Activity: Talk or presentation › Oral presentation

• 光切断特性を有する光クロスリンカーの開発と標的タンパク質蛍光ラベル化への応用

  Chiba, J. (Speaker)

  2015/11/15

  Activity: Talk or presentation › Oral presentation

• ＤＮＡを親水性基としたホスト・ゲスト錯形成型の両親媒性分子の開発

  Chiba, J. (Speaker)

  2015/11/15

  Activity: Talk or presentation › Oral presentation

• A click-type coupling reaction between thioamides and sulfonyl azides as a versatile approach to generate new pharmacologically active compounds

  Chiba, J. (Speaker)

  2015/10/31

  Activity: Talk or presentation › Oral presentation