Keyphrases
Absolute Configuration
11%
Activator protein-1 (AP-1)
24%
Antitumor Activity
12%
Apoptosis
27%
Berberine
11%
Breast Cancer Cells
30%
C-Jun N-terminal Kinase
14%
C-X-C Chemokine Receptor Type 4 (CXCR4)
10%
Cancer Cells
41%
Cancer Metastasis
10%
Cancer Progression
10%
Cell Cycle Arrest
9%
Cell Proliferation
9%
Colon 26
14%
Combination Therapy
9%
Curcumin
14%
CX3CR1
11%
DNA Binding
11%
Endocytosis
15%
Epidermal Growth Factor Receptor
52%
Epidermal Growth Factor Receptor Signaling
16%
ErbB3
10%
Expression Level
11%
Expression Pattern
11%
Extracellular Signal-regulated Kinase
17%
Fibroblast Growth factor-2 (FGF-2)
11%
Gastric Cancer
15%
Gefitinib
12%
Glomerulonephritis
12%
Gomisin N
9%
HeLa Cells
20%
Helicobacter Pylori (H. pylori)
11%
Heme oxygenase-1 (HO-1)
10%
Hepatic Metastasis
11%
Hepatocellular Carcinoma
9%
Human T-cell Leukemia Virus Type 1 (HTLV-1)
11%
Hypoxia
16%
Hypoxia-inducible factor-1α (HIF-1α)
13%
IC50 Value
14%
In Cancer
19%
Induced Activation
18%
Induced Apoptosis
35%
Inflammation
9%
Inhibitory Effect
23%
Interferon Regulatory Factor 4 (IRF4)
10%
Interferon-α (IFN-α)
11%
Interleukin-1β
17%
Juzentaihoto
11%
Kampo Medicine
15%
Keishibukuryogan
11%
Kinase-independent
9%
Knockdown
11%
Lung Metastasis
9%
Lymphatic Endothelial Cells
18%
Melanocytes
17%
Melanoma
38%
Melanoma Cells
18%
Metastasis
28%
Metastatic Potential
11%
Microphthalmia-associated Transcription Factor
17%
Mitogen-activated Protein Kinase
27%
Molecular Mechanism
13%
MRNA Expression
9%
Myeloid Cell leukemia-1 (Mcl-1)
10%
NF-B
93%
Non-canonical
29%
Non-small Cell Lung Cancer (NSCLC)
19%
Nuclear factor-B
47%
Oncogene
9%
Overexpression
9%
P38 Mitogen-activated Protein Kinase (p38 MAPK)
15%
Peritoneal Carcinomatosis
11%
Phosphorylation
89%
Plasma Proteins
12%
Protein Kinase
15%
Receptor Tyrosine Kinase
12%
Receptor-mediated
9%
Signaling Pathway
41%
Small Interfering RNA (siRNA)
9%
TAB2
12%
TAK1
100%
TAK1-Binding Proteins
18%
Threonine
10%
Traditional Japanese Medicine
9%
TRAIL-induced Apoptosis
17%
Transcription Factor
22%
Transforming Growth Factor-β
29%
Triple-negative Breast Cancer Cells
9%
Tumor
10%
Tumor Cell Invasion
11%
Tumor Cells
14%
Tumor Growth
13%
Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)
20%
Tumor Necrosis Factor-α
62%
Tyrosine Kinase Activity
9%
Tyrosine Phosphorylation
11%
Ubc13
11%
Uvaria
9%
Vanillin
9%
Water Extract
9%
Pharmacology, Toxicology and Pharmaceutical Science
Actinobacteria
7%
Alanine Aminopeptidase
7%
Alternative Complement Pathway C3 C5 Convertase
35%
Aminopeptidase Inhibitor
7%
Anti-Inflammatory Drug
7%
Antiangiogenic
8%
Antiapoptotic
10%
Antiinflammatory Activity
11%
Antitumor Activity
7%
Berberine
9%
Binding Protein
15%
Biological Marker
8%
Breast Cancer
31%
C57BL 6 Mouse
7%
Calcium Ion
6%
Cancer Growth
10%
Cancer Growth Factor
23%
Carcinoma
14%
Caspase
8%
Caspase 3
10%
Cell Viability
6%
Chrysin
7%
Cisplatin
12%
Colon Carcinoma
10%
Colorectal Carcinoma
8%
Combination Therapy
13%
Curcumin
11%
Cytokine
14%
Cytotoxicity
10%
Dimer
7%
Enterovirus A71
7%
Epidermal Growth Factor Receptor
74%
Erythropoietin
8%
Experimental Glomerulonephritis
11%
Fibroblast Growth Factor 2
7%
Gefitinib
18%
Gelatinase A
6%
Gelatinase B
8%
Glomerulonephritis
9%
Gomisin
9%
Hachimijiogan
8%
Heat Shock Protein
6%
Helicobacter Pylori
7%
Hirsutine
7%
Human T-Lymphotropic Virus 1
9%
Hyperthermia
11%
Hypoxia
8%
Hypoxia Inducible Factor 1
11%
IC50
9%
Inflammation
16%
Interferon
12%
Interferon Regulatory Factor 3
6%
Interferon Regulatory Factor 4
6%
Kampo Medicine (Drug)
27%
Keishi Bukuryo Gan
12%
Lewis Carcinoma
9%
Liver Cell Carcinoma
12%
Liver Metastasis
8%
Luciferase
11%
Lung Cancer
15%
Lung Metastasis
21%
Malignant Neoplasm
58%
Melanoma
39%
Messenger RNA
15%
Metalloproteinase
7%
Metastasis
16%
Metastasis Potential
9%
Mitogen Activated Protein Kinase
26%
Mitogen Activated Protein Kinase Kinase Kinase
6%
Mitogen Activated Protein Kinase P38
6%
Morus Alba
7%
Mouse Model
7%
Natural Product
6%
Neoplasm
62%
Nitric Oxide
8%
Non Small Cell Lung Cancer
19%
Nuclear Factor
35%
Phosphotransferase
76%
Plasma Protein
12%
Protein Kinases
11%
Protein Tyrosine Kinase
26%
Reactive Oxygen Metabolite
6%
Receptor
25%
Serine
15%
Small Interfering RNA
10%
Streptomyces
7%
Survivin
5%
Synapsin I
12%
Threonine
10%
Transcription Factor AP 1
8%
Transcription Factors
10%
Transforming Growth Factor Beta Activated Kinase 1
8%
Triple Negative Breast Cancer
6%
Tumor Growth
12%
Tumor Necrosis Factor
80%
Tumor Necrosis Factor Related Apoptosis Inducing Ligand
20%
Ubenimex
7%
Uterine Cervix Cancer
7%
Vanillin
9%
Western Blot
10%
Biochemistry, Genetics and Molecular Biology
Akt Signaling
7%
Autophosphorylation
6%
B Cell
11%
Binding Protein
19%
Blood Plasma
11%
C-Terminus
9%
Cancer Cell
54%
Cancer Growth Factor
21%
Caspase 3
6%
Cell Death
11%
Cell Invasion
5%
Cell Migration
12%
Cell Proliferation
7%
Cell Stress
6%
Cell Survival
8%
Chemokine
5%
Cisplatin
11%
Clathrin
5%
Complement Factor B
31%
Cytokine
9%
Cytotoxicity
6%
Deubiquitinating Enzyme
8%
DNA Damage
6%
Downregulation
13%
Endocytosis
15%
Endoplasmic Reticulum Stress
7%
Endothelin Receptor Type B
5%
Epidermal Growth Factor Receptor
55%
Erythropoietin
8%
Extracellular Signal-Regulated Kinases
8%
Fibroblast
10%
Haptoglobin
7%
Heat Shock Protein
8%
Heme Oxygenase
8%
Homeostasis
6%
Human T-Lymphotropic Virus 1
7%
Interferon
11%
Interleukin 6
5%
Interleukin 8
7%
Interleukin-1
19%
IRF4
6%
Isoform
8%
Kinase
61%
Lipocalin
7%
Lymphangiogenesis
5%
MAP Kinase Kinase Kinase
12%
Melanocyte
16%
Messenger RNA
14%
Microphthalmia-Associated Transcription Factor
20%
MicroRNA
7%
Mitogen-Activated Protein Kinase
14%
Mutant Protein
7%
Oncogene
6%
P21
7%
P38 Mitogen-Activated Protein Kinases
20%
Phosphotransferase
60%
Product Inhibition
6%
Promoter Region
11%
Prostaglandin
7%
Proteasome
8%
Protein Kinases
13%
Protein Stability
5%
RANK
5%
RANKL
8%
Receptor Tyrosine Kinase
20%
Secretion (Process)
5%
Serine
24%
Signal Transduction
50%
Small Interfering RNA
14%
STAT1
7%
STAT3
7%
Survivin
5%
Synapsin I
14%
Synthase
7%
T Cell
8%
Threonine
17%
TRAIL
18%
Transactivation
7%
Transcription Factors
14%
Tumor Necrosis Factor
58%
Tumor Necrosis Factor Alpha
7%
Tumor Necrosis Factor Receptor
11%
Tyrosine Kinase
12%
Tyrosine Phosphorylation
6%
Ubiquitination
6%